EGFR is detected as a mutational cancer driver
EGFR reports
Gene details
EGFR |
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Ensembl ID
ENSG00000146648
Transcript ID ENST00000275493 Protein ID ENSP00000275493 |
Cancer types where is driver
9
Cohorts where is driver 14 Mutated samples 383 Mutations 757 |
Mode of action Activating |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
G (Glioma) | 32 | 26 | 81.25 |
GBM (Glioblastoma) | 90 | 63 | 70.00 |
LUAD (Lung adenocarcinoma) | 41 | 29 | 70.73 |
LUNG_CANCER (Lung cancer) | 6 | 0 | 0.00 |
NSCLC (Non-small cell lung cancer) | 43 | 17 | 39.53 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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