IntOGen - COL1A1 gene cancer mutations

COL1A1 is detected as a mutational cancer driver

COL1A1 reports

Methods
Mutation distribution

Gene details

COL1A1
Ensembl ID ENSG00000108821 Transcript ID ENST00000225964 Protein ID ENSP00000225964
Cancer types where is driver 5 Cohorts where is driver 5 Mutated samples 25 Mutations 492
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence