IntOGen - CLTC gene cancer mutations

CLTC is detected as a mutational cancer driver

CLTC reports

Methods
Mutation distribution

Gene details

CLTC
Ensembl ID ENSG00000141367 Transcript ID ENST00000621829 Protein ID ENSP00000479606
Cancer types where is driver 3 Cohorts where is driver 3 Mutated samples 11 Mutations 308
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence