IntOGen - CIITA gene cancer mutations

CIITA is detected as a mutational cancer driver

CIITA reports

Methods
Mutation distribution

Gene details

CIITA
Ensembl ID ENSG00000179583 Transcript ID ENST00000618327 Protein ID ENSP00000485010
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 6 Mutations 372
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence