IntOGen - CBFB gene cancer mutations

CBFB is detected as a mutational cancer driver

CBFB reports

Methods
Mutation distribution

Gene details

CBFB
Ensembl ID ENSG00000067955 Transcript ID ENST00000412916 Protein ID ENSP00000415151
Cancer types where is driver 1 Cohorts where is driver 7 Mutated samples 58 Mutations 145
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence