BRAF is detected as a mutational cancer driver
BRAF reports
Gene details
BRAF |
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Ensembl ID
ENSG00000157764
Transcript ID ENST00000646891 Protein ID ENSP00000493543 |
Cancer types where is driver
19
Cohorts where is driver 43 Mutated samples 1,222 Mutations 1,390 |
Mode of action Activating |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
CM (Cutaneous melanoma of the skin) | 70 | 33 | 47.14 |
COREAD (Colorectal adenocarcinoma) | 28 | 21 | 75.00 |
LUNG_CANCER (Lung cancer) | 4 | 2 | 50.00 |
MM (Multiple myeloma) | 31 | 26 | 83.87 |
NSCLC (Non-small cell lung cancer) | 56 | 29 | 51.79 |
SKIN (Skin cancer) | 15 | 0 | 0.00 |
THCA (Thyroid adenocarcinoma) | 6 | 5 | 83.33 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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