IntOGen - BCLAF1 gene cancer mutations

BCLAF1 is detected as a mutational cancer driver

BCLAF1 reports

Methods
Mutation distribution

Gene details

BCLAF1
Ensembl ID ENSG00000029363 Transcript ID ENST00000531224 Protein ID ENSP00000435210
Cancer types where is driver 3 Cohorts where is driver 3 Mutated samples 36 Mutations 604
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence