ATRX is detected as a mutational cancer driver
ATRX reports
Gene details
ATRX |
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Ensembl ID
ENSG00000085224
Transcript ID ENST00000373344 Protein ID ENSP00000362441 |
Cancer types where is driver
12
Cohorts where is driver 21 Mutated samples 297 Mutations 933 |
Mode of action Loss of function |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
CNS (Central nervous system cancer) | 1 | 0 | 0.00 |
G (Glioma) | 56 | 40 | 71.43 |
LGG (Lower grade glioma) | 90 | 77 | 85.56 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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