IntOGen - ARID1B gene cancer mutations

ARID1B is detected as a mutational cancer driver

ARID1B reports

Methods
Mutation distribution

Gene details

ARID1B
Ensembl ID ENSG00000049618 Transcript ID ENST00000346085 Protein ID ENSP00000344546
Cancer types where is driver 11 Cohorts where is driver 12 Mutated samples 81 Mutations 611
Mode of action Loss of function
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence