APC is detected as a mutational cancer driver
APC reports
Gene details
APC |
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Ensembl ID
ENSG00000134982
Transcript ID ENST00000257430 Protein ID ENSP00000257430 |
Cancer types where is driver
14
Cohorts where is driver 28 Mutated samples 994 Mutations 1,761 |
Mode of action Loss of function |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
COREAD (Colorectal adenocarcinoma) | 414 | 359 | 86.71 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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