IntOGen - ACSL3 gene cancer mutations

ACSL3 is detected as a mutational cancer driver

ACSL3 reports

Methods
Mutation distribution

Gene details

ACSL3
Ensembl ID ENSG00000123983 Transcript ID ENST00000357430 Protein ID ENSP00000350012
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 5 Mutations 217
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence