PIK3CA is detected as a mutational cancer driver in Lung Squamous Cell Carcinoma
PIK3CA reports in Lung Squamous Cell Carcinoma (LUSC)
Cancer type details
| Lung Squamous Cell Carcinoma |
|---|
|
Cohorts
6
Samples 703 Mutations 4,282,647 Driver genes 75 |
Gene details
| PIK3CA |
|---|
|
Ensembl ID
ENSG00000121879
Transcript ID ENST00000263967 Protein ID ENSP00000263967 |
|
Cohorts where is driver
2
Mutated samples 59 Mutated samples (%) 8.39 Mutations 80 |
| Mode of action Activating |
| Known driver True |
Method signals per Cohort
| Cohort | Methods | Samples | Samples (%) |
|---|
ClustL
HotMAPS
smRegions
Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed
mutations along the protein sequence.
| Mutation (GRCh38) | Protein Position | Samples | Samples (%) | Consequence |
|---|