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HLA-B DLBCL ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
6:31356882:T G50D missense_variant 0.94 4
6:31356371:A Q139* stop_gained 1.00 3
6:31356799:A Q78* stop_gained 0.99 3
6:31356865:A Q56* stop_gained 1.00 2
6:31356707:C Y108* stop_gained 1.00 2
6:31356364:A A141V missense_variant 0.63 2
6:31355369:T Y281* stop_gained 1.00 1
6:31355416:A Q266* stop_gained 1.00 1
6:31355383:A E277* stop_gained 0.99 1
6:31356347:C Y147D missense_variant 0.61 1
6:31356179:C L203V missense_variant 0.60 1
6:31355392:A P274S missense_variant 0.60 1
6:31356860:C F57L missense_variant 0.58 1
6:31356862:C F57V missense_variant 0.54 1
6:31356745:A Q96* stop_gained 1.00 0
6:31356700:A Q111* stop_gained 1.00 0
6:31355369:C Y281* stop_gained 1.00 0
6:31356206:A R194* stop_gained 1.00 0
6:31356245:A R181* stop_gained 1.00 0
6:31356214:T W191* stop_gained 1.00 0
6:31356274:T W171* stop_gained 1.00 0
6:31356796:A E79* stop_gained 1.00 0
6:31356201:T Y195* stop_gained 1.00 0
6:31356201:C Y195* stop_gained 1.00 0
6:31356878:C Y51* stop_gained 1.00 0
6:31356878:T Y51* stop_gained 1.00 0
6:31356704:C Y109* stop_gained 1.00 0
6:31356704:T Y109* stop_gained 1.00 0
6:31355386:A G276* stop_gained 1.00 0
6:31355476:A E246* stop_gained 1.00 0
6:31356707:T Y108* stop_gained 1.00 0
6:31355440:A R258* stop_gained 1.00 0
6:31356823:A E70* stop_gained 1.00 0
6:31355446:A E256* stop_gained 1.00 0
6:31356284:A Q168* stop_gained 1.00 0
6:31355431:A G261* stop_gained 1.00 0
6:31356278:A K170* stop_gained 1.00 0
6:31355350:A E288* stop_gained 1.00 0
6:31355506:A E236* stop_gained 1.00 0
6:31355470:A Q248* stop_gained 1.00 0
6:31356272:A E172* stop_gained 1.00 0
6:31355529:T W228* stop_gained 1.00 0
6:31355531:T C227* stop_gained 1.00 0
6:31355464:A Q250* stop_gained 1.00 0
6:31356254:A E178* stop_gained 1.00 0
6:31356213:T W191* stop_gained 1.00 0
6:31356782:T Y83* stop_gained 1.00 0
6:31356782:C Y83* stop_gained 1.00 0
6:31356938:C Y31* stop_gained 1.00 0
6:31356938:T Y31* stop_gained 1.00 0
6:31355528:T W228* stop_gained 1.00 0
6:31356807:T W75* stop_gained 1.00 0
6:31356806:T W75* stop_gained 1.00 0
6:31355363:T C283* stop_gained 1.00 0
6:31355408:T W268* stop_gained 1.00 0
6:31355413:A K267* stop_gained 1.00 0
6:31355425:A R263* stop_gained 1.00 0
6:31356233:A E185* stop_gained 1.00 0
6:31355513:T Y233* stop_gained 1.00 0
6:31355513:C Y233* stop_gained 1.00 0
6:31356315:T W157* stop_gained 1.00 0
6:31356780:T W84* stop_gained 1.00 0
6:31356411:T C125* stop_gained 1.00 0
6:31355409:T W268* stop_gained 1.00 0
6:31356316:T W157* stop_gained 1.00 0
6:31356428:A Q120* stop_gained 1.00 0
6:31356345:T Y147* stop_gained 1.00 0
6:31356345:C Y147* stop_gained 1.00 0
6:31356829:A R68* stop_gained 1.00 0
6:31356237:C Y183* stop_gained 1.00 0
6:31356237:T Y183* stop_gained 1.00 0
6:31355374:A R280* stop_gained 1.00 0
6:31355490:T W241* stop_gained 1.00 0
6:31356779:T W84* stop_gained 1.00 0
6:31355489:T W241* stop_gained 1.00 0
6:31356273:T W171* stop_gained 1.00 0
6:31355319:T W298* stop_gained 1.00 0
6:31355318:T W298* stop_gained 1.00 0
6:31357091:T W23* stop_gained 0.99 0
6:31356188:A K200* stop_gained 0.99 0
6:31355212:A Q303* stop_gained 0.99 0
6:31354660:A K340* stop_gained 0.99 0
6:31355109:C S337* stop_gained 0.99 0
6:31355109:T S337* stop_gained 0.99 0
6:31354657:A G341* stop_gained 0.99 0
6:31355548:A E222* stop_gained 0.99 0
6:31356694:A E113* stop_gained 0.99 0
6:31356888:T S48* stop_gained 0.99 0
6:31356888:C S48* stop_gained 0.99 0
6:31356904:A E43* stop_gained 0.99 0
6:31355317:A E299* stop_gained 0.99 0
6:31356218:A E190* stop_gained 0.99 0
6:31356332:A E152* stop_gained 0.99 0
6:31355488:A Q242* stop_gained 0.99 0
6:31356766:A Q89* stop_gained 0.99 0
6:31356260:A E176* stop_gained 0.99 0
6:31356360:T Y142* stop_gained 0.99 0
6:31356360:C Y142* stop_gained 0.99 0
6:31356227:A E187* stop_gained 0.99 0
6:31356733:A E100* stop_gained 0.99 0
6:31356751:A Q94* stop_gained 0.99 0
6:31356353:A K145* stop_gained 0.99 0
6:31356366:C Y140* stop_gained 0.99 0
6:31356826:A E69* stop_gained 0.99 0
6:31356251:A Q179* stop_gained 0.99 0
6:31356366:T Y140* stop_gained 0.99 0
6:31356417:C Y123* stop_gained 0.99 0
6:31356417:T Y123* stop_gained 0.99 0
6:31356932:C Y33* stop_gained 0.99 0
6:31356932:T Y33* stop_gained 0.99 0
6:31356182:A K202* stop_gained 0.99 0
6:31355455:A E253* stop_gained 0.99 0
6:31356802:A E77* stop_gained 0.99 0
6:31356293:A Q165* stop_gained 0.99 0
6:31356787:A E82* stop_gained 0.99 0
6:31356758:C Y91* stop_gained 0.99 0
6:31356758:T Y91* stop_gained 0.99 0
6:31356736:A R99* stop_gained 0.99 0
6:31355377:A Q279* stop_gained 0.99 0
6:31356757:A K92* stop_gained 0.99 0
6:31355380:A E278* stop_gained 0.99 0
6:31355356:A Q286* stop_gained 0.99 0
6:31356222:T C188* stop_gained 0.99 0
6:31356197:A E197* stop_gained 0.99 0
6:31355116:A K335* stop_gained 0.98 0
6:31355323:A R297* stop_gained 0.98 0
6:31357140:A R7* stop_gained 0.98 0
6:31355123:T C332* stop_gained 0.98 0
6:31355584:A K210* stop_gained 0.98 0
6:31355149:A G324* stop_gained 0.98 0
6:31354646:T Y344* stop_gained 0.98 0
6:31354646:C Y344* stop_gained 0.98 0
6:31354512:A Q354* stop_gained 0.98 0
6:31357098:A E21* stop_gained 0.98 0
6:31355338:A K292* stop_gained 0.98 0
6:31354663:A G339* stop_gained 0.97 0
6:31357118:T S14* stop_gained 0.97 0
6:31357090:T W23* stop_gained 0.97 0
6:31354642:A Q346* stop_gained 0.97 0
6:31354525:T C349* stop_gained 0.97 0
6:31356176:A E204* stop_gained 0.97 0
6:31356882:G G50A missense_variant 0.94 0
6:31356882:A G50V missense_variant 0.94 0
6:31356745:C Q96E missense_variant 0.93 0
6:31356745:T Q96K missense_variant 0.93 0
6:31356319:T S156Y missense_variant 0.93 0
6:31356319:C S156C missense_variant 0.93 0
6:31356319:A S156F missense_variant 0.93 0
6:31356434:A T118S missense_variant 0.93 0
6:31356434:G T118P missense_variant 0.93 0
6:31356434:C T118A missense_variant 0.93 0
6:31355376:A Q279L missense_variant 0.92 0
6:31355376:C Q279R missense_variant 0.92 0
6:31355376:G Q279P missense_variant 0.92 0
6:31355458:A T252S missense_variant 0.90 0
6:31355458:C T252A missense_variant 0.90 0
6:31355458:G T252P missense_variant 0.90 0
6:31356931:A T34S missense_variant 0.90 0
6:31356931:G T34P missense_variant 0.90 0
6:31356931:C T34A missense_variant 0.90 0
6:31356190:T G199E missense_variant 0.89 0
6:31356190:G G199A missense_variant 0.89 0
6:31356190:A G199V missense_variant 0.89 0
6:31356935:T F32L missense_variant 0.85 0
6:31356935:C F32L missense_variant 0.85 0
6:31356700:T Q111K missense_variant 0.85 0
6:31356700:C Q111E missense_variant 0.85 0
6:31356410:T D126N missense_variant 0.85 0
6:31356410:A D126Y missense_variant 0.85 0
6:31356410:G D126H missense_variant 0.85 0
6:31356901:A P44S missense_variant 0.85 0
6:31356901:C P44A missense_variant 0.85 0
6:31356901:T P44T missense_variant 0.85 0
6:31355382:G E277A missense_variant 0.85 0
6:31355382:A E277V missense_variant 0.85 0
6:31355382:C E277G missense_variant 0.85 0
6:31356416:T G124S missense_variant 0.84 0
6:31356416:A G124C missense_variant 0.84 0
6:31356416:G G124R missense_variant 0.84 0
6:31356191:G G199R missense_variant 0.84 0
6:31356191:A G199W missense_variant 0.84 0
6:31356191:T G199R missense_variant 0.84 0
6:31356863:A Q56H missense_variant 0.83 0
6:31356863:G Q56H missense_variant 0.83 0
6:31355370:C Y281C missense_variant 0.83 0
6:31355370:G Y281S missense_variant 0.83 0
6:31355370:A Y281F missense_variant 0.83 0
6:31356912:A G40V missense_variant 0.82 0
6:31356912:T G40D missense_variant 0.82 0
6:31356912:G G40A missense_variant 0.82 0
6:31355514:C Y233C missense_variant 0.82 0
6:31356253:A E178V missense_variant 0.82 0
6:31356253:C E178G missense_variant 0.82 0
6:31356253:G E178A missense_variant 0.82 0
6:31355514:A Y233F missense_variant 0.82 0
6:31355514:G Y233S missense_variant 0.82 0
6:31356820:T P71T missense_variant 0.82 0
6:31356820:C P71A missense_variant 0.82 0
6:31356820:A P71S missense_variant 0.82 0
6:31356435:C H117Q missense_variant 0.81 0
6:31356435:T H117Q missense_variant 0.81 0
6:31356819:T P71Q missense_variant 0.81 0
6:31356819:C P71R missense_variant 0.81 0
6:31356819:A P71L missense_variant 0.81 0
6:31356427:G Q120P missense_variant 0.81 0
6:31356427:A Q120L missense_variant 0.81 0
6:31356427:C Q120R missense_variant 0.81 0
6:31355461:A D251Y missense_variant 0.81 0
6:31355461:T D251N missense_variant 0.81 0
6:31355461:G D251H missense_variant 0.81 0
6:31356848:C D61E missense_variant 0.80 0
6:31356848:T D61E missense_variant 0.80 0
6:31356206:C R194G missense_variant 0.78 0
6:31356845:C S62R missense_variant 0.78 0
6:31356845:T S62R missense_variant 0.78 0
6:31356325:G L154P missense_variant 0.74 0
6:31356325:T L154Q missense_variant 0.74 0
6:31356325:C L154R missense_variant 0.74 0
6:31356728:C S101R missense_variant 0.73 0
6:31356728:T S101R missense_variant 0.73 0
6:31356275:G W171R missense_variant 0.73 0
6:31356275:T W171R missense_variant 0.73 0
6:31356275:C W171G missense_variant 0.73 0
6:31356168:C A206A splice_region_variant 0.73 0
6:31356168:G A206A splice_region_variant 0.73 0
6:31356168:T A206A splice_region_variant 0.73 0
6:31356703:A N110Y missense_variant 0.70 0
6:31356703:G N110H missense_variant 0.70 0
6:31356703:C N110D missense_variant 0.70 0
6:31356334:C N151S missense_variant 0.69 0
6:31356334:A N151I missense_variant 0.69 0
6:31356334:G N151T missense_variant 0.69 0
6:31355503:A I237F missense_variant 0.69 0
6:31355503:G I237L missense_variant 0.69 0
6:31355503:C I237V missense_variant 0.69 0
6:31355553:A D220V missense_variant 0.67 0
6:31355553:C D220G missense_variant 0.67 0
6:31355553:G D220A missense_variant 0.67 0
6:31354493:C L360R missense_variant 0.67 0
6:31354493:G L360P missense_variant 0.67 0
6:31354493:T L360H missense_variant 0.67 0
6:31356215:G W191R missense_variant 0.66 0
6:31356215:T W191R missense_variant 0.66 0
6:31356215:C W191G missense_variant 0.66 0
6:31356193:A N198I missense_variant 0.66 0
6:31356193:G N198T missense_variant 0.66 0
6:31356193:C N198S missense_variant 0.66 0
6:31356282:A Q168H missense_variant 0.66 0
6:31356282:G Q168H missense_variant 0.66 0
6:31356821:G E70D missense_variant 0.66 0
6:31356821:A E70D missense_variant 0.66 0
6:31356383:A R135C missense_variant 0.66 0
6:31356383:C R135G missense_variant 0.66 0
6:31356383:T R135S missense_variant 0.66 0
6:31355379:A E278V missense_variant 0.65 0
6:31355379:G E278A missense_variant 0.65 0
6:31355379:C E278G missense_variant 0.65 0
6:31356850:A D61Y missense_variant 0.63 0
6:31356850:G D61H missense_variant 0.63 0
6:31356850:T D61N missense_variant 0.63 0
6:31356245:C R181G missense_variant 0.63 0
6:31356422:A M122L missense_variant 0.63 0
6:31356422:C M122V missense_variant 0.63 0
6:31356422:G M122L missense_variant 0.63 0
6:31355474:G E246D missense_variant 0.63 0
6:31355474:A E246D missense_variant 0.63 0
6:31356394:A G131V missense_variant 0.63 0
6:31356394:G G131A missense_variant 0.63 0
6:31356394:T G131E missense_variant 0.63 0
6:31356203:T Y195N missense_variant 0.63 0
6:31356203:G Y195H missense_variant 0.63 0
6:31356203:C Y195D missense_variant 0.63 0
6:31356364:C A141G missense_variant 0.63 0
6:31356364:T A141D missense_variant 0.63 0
6:31355398:T V272M missense_variant 0.63 0
6:31355398:A V272L missense_variant 0.63 0
6:31355398:G V272L missense_variant 0.63 0
6:31356709:G Y108H missense_variant 0.62 0
6:31356709:T Y108N missense_variant 0.62 0
6:31356709:C Y108D missense_variant 0.62 0
6:31356844:T D63N missense_variant 0.62 0
6:31356844:G D63H missense_variant 0.62 0
6:31356844:A D63Y missense_variant 0.62 0
6:31356695:C S112R missense_variant 0.62 0
6:31356288:C I166M missense_variant 0.62 0
6:31356695:T S112R missense_variant 0.62 0
6:31356699:A Q111L missense_variant 0.62 0
6:31356699:C Q111R missense_variant 0.62 0
6:31356699:G Q111P missense_variant 0.62 0
6:31355531:C C227W missense_variant 0.62 0
6:31356945:T M29K missense_variant 0.62 0
6:31356945:C M29R missense_variant 0.62 0
6:31356945:G M29T missense_variant 0.62 0
6:31356252:G E178D missense_variant 0.62 0
6:31356252:A E178D missense_variant 0.62 0
6:31356342:C I148M missense_variant 0.62 0
6:31356794:G E79D missense_variant 0.61 0
6:31356794:A E79D missense_variant 0.61 0
6:31355464:C Q250E missense_variant 0.61 0
6:31355464:T Q250K missense_variant 0.61 0
6:31356955:T S26T missense_variant 0.61 0
6:31356955:G S26P missense_variant 0.61 0
6:31356955:C S26A missense_variant 0.61 0
6:31356778:T D85N missense_variant 0.61 0
6:31356778:G D85H missense_variant 0.61 0
6:31356778:A D85Y missense_variant 0.61 0
6:31356317:C W157G missense_variant 0.61 0
6:31356317:G W157R missense_variant 0.61 0
6:31356317:T W157R missense_variant 0.61 0
6:31356347:T Y147N missense_variant 0.61 0
6:31356347:G Y147H missense_variant 0.61 0
6:31356806:G W75C missense_variant 0.61 0
6:31356807:A W75L missense_variant 0.61 0
6:31356807:G W75S missense_variant 0.61 0
6:31356806:A W75C missense_variant 0.61 0
6:31356337:T L150Q missense_variant 0.61 0
6:31356337:C L150R missense_variant 0.61 0
6:31356337:G L150P missense_variant 0.61 0
6:31355352:A H287L missense_variant 0.61 0
6:31355352:G H287P missense_variant 0.61 0
6:31355352:C H287R missense_variant 0.61 0
6:31356361:G Y142S missense_variant 0.61 0
6:31356361:A Y142F missense_variant 0.61 0
6:31356361:C Y142C missense_variant 0.61 0
6:31356238:A Y183F missense_variant 0.60 0
6:31356238:C Y183C missense_variant 0.60 0
6:31356238:G Y183S missense_variant 0.60 0
6:31356873:G D53A missense_variant 0.60 0
6:31356873:C D53G missense_variant 0.60 0
6:31356873:A D53V missense_variant 0.60 0
6:31356951:A H27L missense_variant 0.60 0
6:31356951:C H27R missense_variant 0.60 0
6:31356951:G H27P missense_variant 0.60 0
6:31356179:T L203M missense_variant 0.60 0
6:31356274:G W171S missense_variant 0.60 0
6:31356274:A W171L missense_variant 0.60 0
6:31356187:C K200R missense_variant 0.60 0
6:31356187:G K200T missense_variant 0.60 0
6:31356187:A K200M missense_variant 0.60 0
6:31355485:A R243W missense_variant 0.60 0
6:31355485:C R243G missense_variant 0.60 0
6:31356296:A A164S missense_variant 0.60 0
6:31356296:T A164T missense_variant 0.60 0
6:31356296:G A164P missense_variant 0.60 0
6:31355392:C P274A missense_variant 0.60 0
6:31355392:T P274T missense_variant 0.60 0
6:31355482:T D244N missense_variant 0.60 0
6:31355482:G D244H missense_variant 0.60 0
6:31355482:A D244Y missense_variant 0.60 0
6:31356328:C D153G missense_variant 0.59 0
6:31356328:A D153V missense_variant 0.59 0
6:31356328:G D153A missense_variant 0.59 0
6:31356726:T L102Q missense_variant 0.59 0
6:31356726:C L102R missense_variant 0.59 0
6:31356726:G L102P missense_variant 0.59 0
6:31356426:G Q120H missense_variant 0.59 0
6:31356426:A Q120H missense_variant 0.59 0
6:31356200:T L196M missense_variant 0.59 0
6:31356200:C L196V missense_variant 0.59 0
6:31356854:A R59S missense_variant 0.59 0
6:31356854:G R59S missense_variant 0.59 0
6:31355439:T R258K missense_variant 0.59 0
6:31355414:G Q266H missense_variant 0.59 0
6:31355414:A Q266H missense_variant 0.59 0
6:31355439:G R258T missense_variant 0.59 0
6:31355439:A R258I missense_variant 0.59 0
6:31355444:G E256D missense_variant 0.59 0
6:31355523:T L230Q missense_variant 0.59 0
6:31355523:G L230P missense_variant 0.59 0
6:31355523:C L230R missense_variant 0.59 0
6:31355444:A E256D missense_variant 0.59 0
6:31355434:T A260T missense_variant 0.59 0
6:31355434:G A260P missense_variant 0.59 0
6:31355434:A A260S missense_variant 0.59 0
6:31356420:T M122I missense_variant 0.59 0
6:31356420:A M122I missense_variant 0.59 0
6:31356420:G M122I missense_variant 0.59 0
6:31356922:T S37T missense_variant 0.59 0
6:31356922:G S37P missense_variant 0.59 0
6:31356922:C S37A missense_variant 0.59 0
6:31356860:T F57L missense_variant 0.58 0
6:31356214:G W191S missense_variant 0.58 0
6:31356214:A W191L missense_variant 0.58 0
6:31355463:G Q250P missense_variant 0.58 0
6:31355463:A Q250L missense_variant 0.58 0
6:31355463:C Q250R missense_variant 0.58 0
6:31355530:G W228R missense_variant 0.58 0
6:31355530:C W228G missense_variant 0.58 0
6:31355530:T W228R missense_variant 0.58 0
6:31354506:T S356T missense_variant 0.58 0
6:31354506:G S356P missense_variant 0.58 0
6:31354506:C S356A missense_variant 0.58 0
6:31356777:A D85V missense_variant 0.58 0
6:31356777:C D85G missense_variant 0.58 0
6:31356777:G D85A missense_variant 0.58 0
6:31357096:G E21D missense_variant 0.57 0
6:31357096:A E21D missense_variant 0.57 0
6:31356763:G I90L missense_variant 0.57 0
6:31356763:C I90V missense_variant 0.57 0
6:31356763:A I90F missense_variant 0.57 0
6:31356244:A R181I missense_variant 0.57 0
6:31356244:G R181T missense_variant 0.57 0
6:31356244:T R181K missense_variant 0.57 0
6:31355545:A A223S missense_variant 0.57 0
6:31355545:T A223T missense_variant 0.57 0
6:31355545:G A223P missense_variant 0.57 0
6:31356865:C Q56E missense_variant 0.57 0
6:31356865:T Q56K missense_variant 0.57 0
6:31356895:G F46L missense_variant 0.57 0
6:31356895:T F46I missense_variant 0.57 0
6:31356895:C F46V missense_variant 0.57 0
6:31356885:T V49E missense_variant 0.57 0
6:31356885:C V49G missense_variant 0.57 0
6:31356702:C N110S missense_variant 0.57 0
6:31356702:A N110I missense_variant 0.57 0
6:31356702:G N110T missense_variant 0.57 0
6:31356885:G V49A missense_variant 0.57 0
6:31356937:T F32I missense_variant 0.57 0
6:31356937:C F32V missense_variant 0.57 0
6:31356937:G F32L missense_variant 0.57 0
6:31356940:G Y31H missense_variant 0.57 0
6:31356940:T Y31N missense_variant 0.57 0
6:31356940:C Y31D missense_variant 0.57 0
6:31355556:A S219F missense_variant 0.56 0
6:31355556:C S219C missense_variant 0.56 0
6:31355556:T S219Y missense_variant 0.56 0
6:31356861:C F57C missense_variant 0.56 0
6:31356861:T F57Y missense_variant 0.56 0
6:31356861:G F57S missense_variant 0.56 0
6:31355416:C Q266E missense_variant 0.56 0
6:31355416:T Q266K missense_variant 0.56 0
6:31356808:G W75R missense_variant 0.56 0
6:31356808:C W75G missense_variant 0.56 0
6:31356808:T W75R missense_variant 0.56 0
6:31355386:T G276R missense_variant 0.56 0
6:31355386:G G276R missense_variant 0.56 0
6:31355410:T W268R missense_variant 0.56 0
6:31355410:C W268G missense_variant 0.56 0
6:31355410:G W268R missense_variant 0.56 0
6:31356924:C V36G missense_variant 0.56 0
6:31356924:T V36E missense_variant 0.56 0
6:31356924:G V36A missense_variant 0.56 0
6:31356780:A W84L missense_variant 0.56 0
6:31356780:G W84S missense_variant 0.56 0
6:31356310:C A159G missense_variant 0.56 0
6:31356310:A A159V missense_variant 0.56 0
6:31356310:T A159D missense_variant 0.56 0
6:31356371:C Q139E missense_variant 0.55 0
6:31356371:T Q139K missense_variant 0.55 0
6:31356706:G Y109H missense_variant 0.55 0
6:31356706:C Y109D missense_variant 0.55 0
6:31356706:T Y109N missense_variant 0.55 0
6:31355580:C T211R missense_variant 0.55 0
6:31355580:T T211K missense_variant 0.55 0
6:31355580:A T211I missense_variant 0.55 0
6:31354648:C Y344D missense_variant 0.55 0
6:31354648:G Y344H missense_variant 0.55 0
6:31354648:T Y344N missense_variant 0.55 0
6:31355415:C Q266R missense_variant 0.55 0
6:31355415:A Q266L missense_variant 0.55 0
6:31355415:G Q266P missense_variant 0.55 0
6:31355526:A A229V missense_variant 0.55 0
6:31355526:T A229D missense_variant 0.55 0
6:31356907:T G42R missense_variant 0.55 0
6:31356907:G G42R missense_variant 0.55 0
6:31356907:A G42W missense_variant 0.55 0
6:31355526:C A229G missense_variant 0.55 0
6:31356936:C F32C missense_variant 0.55 0
6:31356936:T F32Y missense_variant 0.55 0
6:31356936:G F32S missense_variant 0.55 0
6:31355481:C D244G missense_variant 0.54 0
6:31355481:G D244A missense_variant 0.54 0
6:31355481:A D244V missense_variant 0.54 0
6:31356804:G I76T missense_variant 0.54 0
6:31356804:T I76K missense_variant 0.54 0
6:31356804:C I76R missense_variant 0.54 0
6:31355515:C Y233D missense_variant 0.54 0
6:31355515:G Y233H missense_variant 0.54 0
6:31355515:T Y233N missense_variant 0.54 0
6:31356419:C Y123D missense_variant 0.54 0
6:31356419:T Y123N missense_variant 0.54 0
6:31356419:G Y123H missense_variant 0.54 0
6:31356915:A P39L missense_variant 0.54 0
6:31356915:T P39H missense_variant 0.54 0
6:31356915:C P39R missense_variant 0.54 0
6:31355427:A D262V missense_variant 0.54 0
6:31355427:C D262G missense_variant 0.54 0
6:31355427:G D262A missense_variant 0.54 0
6:31355371:T Y281N missense_variant 0.54 0
6:31355371:G Y281H missense_variant 0.54 0
6:31355371:C Y281D missense_variant 0.54 0
6:31356398:G D130H missense_variant 0.54 0
6:31356398:T D130N missense_variant 0.54 0
6:31356398:A D130Y missense_variant 0.54 0
6:31356796:T E79K missense_variant 0.54 0
6:31356796:G E79Q missense_variant 0.54 0
6:31355355:C Q286R missense_variant 0.54 0
6:31355355:A Q286L missense_variant 0.54 0
6:31355355:G Q286P missense_variant 0.54 0
6:31356433:A T118I missense_variant 0.54 0
6:31356433:C T118S missense_variant 0.54 0
6:31356433:T T118N missense_variant 0.54 0
6:31356862:G F57L missense_variant 0.54 0
6:31356862:T F57I missense_variant 0.54 0
6:31356957:T G25D missense_variant 0.54 0
6:31356957:A G25V missense_variant 0.54 0
6:31356957:G G25A missense_variant 0.54 0
6:31355520:T G231D missense_variant 0.54 0
6:31355520:A G231V missense_variant 0.54 0
6:31355520:G G231A missense_variant 0.54 0
6:31355516:C F232L missense_variant 0.54 0
6:31355516:T F232L missense_variant 0.54 0
6:31356711:A G107V missense_variant 0.54 0
6:31356711:T G107D missense_variant 0.54 0
6:31356711:G G107A missense_variant 0.54 0
6:31356880:G Y51H missense_variant 0.54 0
6:31356880:C Y51D missense_variant 0.54 0
6:31356880:T Y51N missense_variant 0.54 0
6:31356428:C Q120E missense_variant 0.53 0
6:31356428:T Q120K missense_variant 0.53 0
6:31356439:A S116F missense_variant 0.53 0
6:31356439:C S116C missense_variant 0.53 0
6:31356439:T S116Y missense_variant 0.53 0
6:31355460:G D251A missense_variant 0.53 0
6:31355460:C D251G missense_variant 0.53 0
6:31355460:A D251V missense_variant 0.53 0
6:31356406:G V127A missense_variant 0.53 0
6:31356406:C V127G missense_variant 0.53 0
6:31356406:T V127E missense_variant 0.53 0
6:31356286:A T167I missense_variant 0.53 0
6:31356286:T T167N missense_variant 0.53 0
6:31356286:C T167S missense_variant 0.53 0
6:31355346:G G289A missense_variant 0.53 0
6:31355346:A G289V missense_variant 0.53 0
6:31355346:T G289E missense_variant 0.53 0
6:31355421:C T264S missense_variant 0.53 0
6:31355421:A T264I missense_variant 0.53 0
6:31355421:T T264N missense_variant 0.53 0
6:31356768:A T88I missense_variant 0.53 0
6:31356768:C T88R missense_variant 0.53 0
6:31356768:T T88K missense_variant 0.53 0
6:31355442:A T257I missense_variant 0.53 0
6:31355442:C T257S missense_variant 0.53 0
6:31355442:T T257N missense_variant 0.53 0
6:31356379:A G136V missense_variant 0.53 0
6:31356379:G G136A missense_variant 0.53 0
6:31356379:T G136E missense_variant 0.53 0
6:31354665:T G338D missense_variant 0.53 0
6:31354665:A G338V missense_variant 0.53 0
6:31354665:G G338A missense_variant 0.53 0
6:31356793:T G80R missense_variant 0.52 0
6:31356793:G G80R missense_variant 0.52 0
6:31356793:A G80W missense_variant 0.52 0
6:31356883:T G50S missense_variant 0.52 0
6:31356883:G G50R missense_variant 0.52 0
6:31356883:A G50C missense_variant 0.52 0
6:31355440:C R258G missense_variant 0.52 0
6:31356918:T R38Q missense_variant 0.52 0
6:31356918:A R38L missense_variant 0.52 0
6:31356918:G R38P missense_variant 0.52 0
6:31355486:A Q242H missense_variant 0.51 0
6:31355486:G Q242H missense_variant 0.51 0
6:31355422:A T264S missense_variant 0.51 0
6:31355422:C T264A missense_variant 0.51 0
6:31355422:G T264P missense_variant 0.51 0
6:31355446:G E256Q missense_variant 0.51 0
6:31355446:T E256K missense_variant 0.51 0
6:31355473:A D247Y missense_variant 0.51 0
6:31355473:T D247N missense_variant 0.51 0
6:31355473:G D247H missense_variant 0.51 0
6:31355479:G G245R missense_variant 0.51 0
6:31355479:T G245S missense_variant 0.51 0
6:31355479:A G245C missense_variant 0.51 0
6:31356950:C H27Q missense_variant 0.51 0
6:31356950:T H27Q missense_variant 0.51 0
6:31356822:A E70V missense_variant 0.51 0
6:31356822:C E70G missense_variant 0.51 0
6:31356822:G E70A missense_variant 0.51 0
6:31355476:G E246Q missense_variant 0.51 0
6:31355476:T E246K missense_variant 0.51 0
6:31356869:C D54E missense_variant 0.50 0
6:31356869:T D54E missense_variant 0.50 0
6:31356430:G L119P missense_variant 0.50 0
6:31356430:C L119R missense_variant 0.50 0
6:31356430:T L119H missense_variant 0.50 0
6:31356284:C Q168E missense_variant 0.50 0
6:31356284:T Q168K missense_variant 0.50 0
6:31356769:A T88S missense_variant 0.50 0
6:31356769:C T88A missense_variant 0.50 0
6:31356769:G T88P missense_variant 0.50 0
6:31354505:C S356C missense_variant 0.50 0
6:31354505:A S356F missense_variant 0.50 0
6:31354505:T S356Y missense_variant 0.50 0
6:31356257:A A177S missense_variant 0.50 0
6:31356257:T A177T missense_variant 0.50 0
6:31356257:G A177P missense_variant 0.50 0
6:31356167:G D207H missense_variant 0.50 0
6:31356167:A D207Y missense_variant 0.50 0
6:31356167:T D207N missense_variant 0.50 0
6:31355566:A H216Y missense_variant 0.50 0
6:31355566:T H216N missense_variant 0.50 0
6:31355566:C H216D missense_variant 0.50 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(DLBCL) Diffuse large B-cell lymphoma CANCER 0.55 0.18