Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.
| Feature
|
Feature value
|
SHAP value
|
| Linear Clustering Score (LCS) |
780.77 |
-0.31
Medium negative
|
| Linear Clustering in Cancer Type (LCT) |
0.00 |
-0.05
Non-significant
|
| Linear Clustering (LC) |
1.00 |
0.05
Non-significant
|
| 3D Clustering in Cancer Type (3CT) |
0.00 |
-0.48
Medium negative
|
| 3D clustering (3C) |
1.00 |
0.21
Medium positive
|
| Recurrent in PFAM Domain (DOM) |
1.00 |
0.08
Non-significant
|
| Recurrent in PFAM Domain v2 (DOM2) |
0.00 |
-0.05
Non-significant
|
| PhyloP 100-way Score (PHYLOP) |
8.02 |
-0.08
Non-significant
|
| Stop Codon in Last Exon (NMD) |
0.00 |
0.00
Non-significant
|
| Post-translational Modification Site: Acetylation (ACETYLATION) |
1.00 |
0.00
Non-significant
|
| Post-translational Modification Site: Methylation (METHYLATION) |
0.00 |
-0.01
Non-significant
|
| Post-translational Modification Site: Phosphorylation (PHOS) |
0.00 |
0.04
Non-significant
|
| Post-translational Modification Site: Regulatory site (REG) |
1.00 |
-0.41
Medium negative
|
| Post-translational Modification Site: Ubiquitination (UB) |
1.00 |
0.17
Medium positive
|
| Consequence Type: Missense (MISSENSE) |
0.00 |
-0.93
Medium negative
|
| Consequence Type: Nonsense (NONSENSE) |
1.00 |
2.59
High positive
|
| Consequence Type: Splice-affecting (SPLICE) |
0.00 |
-0.19
Medium negative
|
| Consequence Type: Synonymous (SYNONYMOUS) |
0.00 |
0.00
Non-significant
|