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Note:
You're navigating the results of models obtained with the previous release of
IntOGen (2020)
. A new boostDM version corresponding to the current IntOGen release will be available soon.
TP53
17:7674939:A (E198*)
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Driver potential
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Model
BoostDM class
BoostDM score
(AML) Acute myeloid leukemia
Passenger
0.42
(BLCA) Bladder cancer
Driver
1.00
(BRCA) Breast adenocarcinoma
Driver
0.98
(CH) Cholangiocarcinoma
Driver
0.98
(CLL) Chronic lymphoblastic leukemia
Passenger
0.41
(CM) Cutaneous melanoma of the skin
Driver
0.99
(COREAD) Colorectal adenocarcinoma
Driver
0.85
(DLBCL) Diffuse large B-cell lymphoma
Driver
0.88
(ESCA) Esophageal cancer
Driver
0.99
(GBM) Glioblastoma
Driver
0.63
(HC) Hepatic cancer
Driver
0.98
(HGG) High-grade glioma
Driver
0.53
(HNSC) Head and neck squamous cell carcinoma
Driver
0.99
(LEIS) Leiomyosarcoma
Driver
0.94
(LGG) Lower grade glioma
Driver
0.74
(LUAD) Lung adenocarcinoma
Driver
1.00
(LUNG_CANCER) Lung cancer
Driver
1.00
(LUSC) Lung squamous cell carcinoma
Driver
1.00
(LY) Lymphoma
Driver
0.86
(MM) Multiple myeloma
Driver
0.94
(NHLY) Non-hodking lymphoma
Driver
0.92
(OS) Osteosarcoma
Passenger
0.37
(OV) Ovary cancer
Driver
0.97
(PAAD) Pancreas adenocarcinoma
Driver
0.87
(PIA) Pilocityc astrocytoma
Passenger
0.01
(PRAD) Prostate adenocarcinoma
Driver
0.91
(R) Kidney cancer
Driver
0.99
(RCCC) Renal clear cell carcinoma
Driver
0.99
(RCH) Chromophobe renal cell carcinoma
Driver
0.99
(S) Sarcoma
Driver
0.94
(SCLC) Small-cell lung cancer
Driver
0.97
(ST) Stomach adenocarcinoma
Driver
0.99
(UCEC) Endometrial cancer
Driver
0.89
(UCS) Uterine carcinosarcoma
Driver
0.88
Select a tumor type to check the corresponding model
Show the legend
Predictions cast with a model trained in this specific tumor type.
Predictions cast with a model trained with a more general tumor type, determined as the most recent
underlined
ancestor of the leaf.
Driver
The mutation is predicted to be a driver in this tumor type context.
Passenger
The mutation is predicted to be a passenger in this tumor type context.
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(CANCER) Cancer
(SOLID) Solid tumour
(S) Sarcoma
(UCS) Uterine carcinosarcoma
Driver
(OS) Osteosarcoma
Passenger
(LEIS) Leiomyosarcoma
Driver
(UCEC) Endometrial cancer
Driver
(ST) Stomach adenocarcinoma
Driver
(LUNG_CANCER) Lung cancer
(SCLC) Small-cell lung cancer
Driver
(NSCLC) Non-small cell lung cancer
(LUSC) Lung squamous cell carcinoma
Driver
(LUAD) Lung adenocarcinoma
Driver
(R) Kidney cancer
(RCH) Chromophobe renal cell carcinoma
Driver
(RCCC) Renal clear cell carcinoma
Driver
(PRAD) Prostate adenocarcinoma
Driver
(CNS) Central nervous system cancer
(G) Glioma
(PIA) Pilocityc astrocytoma
Passenger
(LGG) Lower grade glioma
Driver
(HGG) High-grade glioma
Driver
(GBM) Glioblastoma
Driver
(PA) Pancreatic cancer
(PAAD) Pancreas adenocarcinoma
Driver
(OV) Ovary cancer
Driver
(HNSC) Head and neck squamous cell carcinoma
Driver
(LIVER) LIVER
(HC) Hepatic cancer
Driver
(ESCA) Esophageal cancer
Driver
(COREAD) Colorectal adenocarcinoma
Driver
(SKIN) Skin cancer
(CM) Cutaneous melanoma of the skin
Driver
(CH) Cholangiocarcinoma
Driver
(BRCA) Breast adenocarcinoma
Driver
(BLCA) Bladder cancer
Driver
(NON_SOLID) Non-Solid cancer
(L) Lymphoid cancer
(LY) Lymphoma
(NHLY) Non-hodking lymphoma
Driver
(DLBCL) Diffuse large B-cell lymphoma
Driver
(LK) Leukemia
(CLL) Chronic lymphoblastic leukemia
Passenger
(AML) Acute myeloid leukemia
Passenger
(MM) Multiple myeloma
Driver