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Note:
You're navigating the results of models obtained with the previous release of
IntOGen (2020)
. A new boostDM version corresponding to the current IntOGen release will be available soon.
TP53
17:7674246:C (N239K)
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Driver potential
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Model
BoostDM class
BoostDM score
(AML) Acute myeloid leukemia
Passenger
0.49
(BLCA) Bladder cancer
Passenger
0.04
(BRCA) Breast adenocarcinoma
Driver
1.00
(CH) Cholangiocarcinoma
Driver
0.65
(CLL) Chronic lymphoblastic leukemia
Driver
0.98
(CM) Cutaneous melanoma of the skin
Passenger
0.03
(COREAD) Colorectal adenocarcinoma
Driver
1.00
(DLBCL) Diffuse large B-cell lymphoma
Driver
1.00
(ESCA) Esophageal cancer
Driver
1.00
(GBM) Glioblastoma
Passenger
0.28
(HC) Hepatic cancer
Passenger
0.36
(HGG) High-grade glioma
Passenger
0.48
(HNSC) Head and neck squamous cell carcinoma
Driver
0.98
(LEIS) Leiomyosarcoma
Passenger
0.39
(LGG) Lower grade glioma
Passenger
0.00
(LUAD) Lung adenocarcinoma
Driver
0.96
(LUNG_CANCER) Lung cancer
Passenger
0.33
(LUSC) Lung squamous cell carcinoma
Passenger
0.05
(LY) Lymphoma
Driver
0.53
(MM) Multiple myeloma
Passenger
0.25
(NHLY) Non-hodking lymphoma
Driver
0.55
(OS) Osteosarcoma
Driver
0.89
(OV) Ovary cancer
Driver
0.99
(PAAD) Pancreas adenocarcinoma
Driver
1.00
(PIA) Pilocityc astrocytoma
Passenger
0.44
(PRAD) Prostate adenocarcinoma
Driver
0.99
(R) Kidney cancer
Driver
0.65
(RCCC) Renal clear cell carcinoma
Driver
0.65
(RCH) Chromophobe renal cell carcinoma
Driver
0.96
(S) Sarcoma
Passenger
0.39
(SCLC) Small-cell lung cancer
Driver
0.99
(ST) Stomach adenocarcinoma
Passenger
0.03
(UCEC) Endometrial cancer
Driver
1.00
(UCS) Uterine carcinosarcoma
Driver
1.00
Select a tumor type to check the corresponding model
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Predictions cast with a model trained in this specific tumor type.
Predictions cast with a model trained with a more general tumor type, determined as the most recent
underlined
ancestor of the leaf.
Driver
The mutation is predicted to be a driver in this tumor type context.
Passenger
The mutation is predicted to be a passenger in this tumor type context.
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(CANCER) Cancer
(SOLID) Solid tumour
(S) Sarcoma
(UCS) Uterine carcinosarcoma
Driver
(OS) Osteosarcoma
Driver
(LEIS) Leiomyosarcoma
Passenger
(UCEC) Endometrial cancer
Driver
(ST) Stomach adenocarcinoma
Passenger
(LUNG_CANCER) Lung cancer
(SCLC) Small-cell lung cancer
Driver
(NSCLC) Non-small cell lung cancer
(LUSC) Lung squamous cell carcinoma
Passenger
(LUAD) Lung adenocarcinoma
Driver
(R) Kidney cancer
(RCH) Chromophobe renal cell carcinoma
Driver
(RCCC) Renal clear cell carcinoma
Driver
(PRAD) Prostate adenocarcinoma
Driver
(CNS) Central nervous system cancer
(G) Glioma
(PIA) Pilocityc astrocytoma
Passenger
(LGG) Lower grade glioma
Passenger
(HGG) High-grade glioma
Passenger
(GBM) Glioblastoma
Passenger
(PA) Pancreatic cancer
(PAAD) Pancreas adenocarcinoma
Driver
(OV) Ovary cancer
Driver
(HNSC) Head and neck squamous cell carcinoma
Driver
(LIVER) LIVER
(HC) Hepatic cancer
Passenger
(ESCA) Esophageal cancer
Driver
(COREAD) Colorectal adenocarcinoma
Driver
(SKIN) Skin cancer
(CM) Cutaneous melanoma of the skin
Passenger
(CH) Cholangiocarcinoma
Driver
(BRCA) Breast adenocarcinoma
Driver
(BLCA) Bladder cancer
Passenger
(NON_SOLID) Non-Solid cancer
(L) Lymphoid cancer
(LY) Lymphoma
(NHLY) Non-hodking lymphoma
Driver
(DLBCL) Diffuse large B-cell lymphoma
Driver
(LK) Leukemia
(CLL) Chronic lymphoblastic leukemia
Driver
(AML) Acute myeloid leukemia
Passenger
(MM) Multiple myeloma
Passenger