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Note:
You're navigating the results of models obtained with the previous release of
IntOGen (2020)
. A new boostDM version corresponding to the current IntOGen release will be available soon.
TP53
17:7673769:C (T284R)
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Driver potential
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Model
BoostDM class
BoostDM score
(AML) Acute myeloid leukemia
Driver
0.99
(BLCA) Bladder cancer
Passenger
0.18
(BRCA) Breast adenocarcinoma
Passenger
0.13
(CH) Cholangiocarcinoma
Driver
0.91
(CLL) Chronic lymphoblastic leukemia
Driver
1.00
(CM) Cutaneous melanoma of the skin
Passenger
0.17
(COREAD) Colorectal adenocarcinoma
Passenger
0.02
(DLBCL) Diffuse large B-cell lymphoma
Driver
0.82
(ESCA) Esophageal cancer
Passenger
0.16
(GBM) Glioblastoma
Driver
0.94
(HC) Hepatic cancer
Driver
0.98
(HGG) High-grade glioma
Driver
0.93
(HNSC) Head and neck squamous cell carcinoma
Passenger
0.03
(LEIS) Leiomyosarcoma
Driver
0.98
(LGG) Lower grade glioma
Passenger
0.01
(LUAD) Lung adenocarcinoma
Driver
0.95
(LUNG_CANCER) Lung cancer
Driver
0.99
(LUSC) Lung squamous cell carcinoma
Passenger
0.08
(LY) Lymphoma
Driver
0.96
(MM) Multiple myeloma
Driver
0.81
(NHLY) Non-hodking lymphoma
Driver
0.96
(OS) Osteosarcoma
Driver
0.99
(OV) Ovary cancer
Passenger
0.06
(PAAD) Pancreas adenocarcinoma
Passenger
0.24
(PIA) Pilocityc astrocytoma
Passenger
0.48
(PRAD) Prostate adenocarcinoma
Driver
0.96
(R) Kidney cancer
Driver
0.83
(RCCC) Renal clear cell carcinoma
Driver
0.83
(RCH) Chromophobe renal cell carcinoma
Passenger
0.17
(S) Sarcoma
Driver
0.98
(SCLC) Small-cell lung cancer
Driver
0.98
(ST) Stomach adenocarcinoma
Driver
0.95
(UCEC) Endometrial cancer
Driver
0.87
(UCS) Uterine carcinosarcoma
Driver
0.85
Select a tumor type to check the corresponding model
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Predictions cast with a model trained in this specific tumor type.
Predictions cast with a model trained with a more general tumor type, determined as the most recent
underlined
ancestor of the leaf.
Driver
The mutation is predicted to be a driver in this tumor type context.
Passenger
The mutation is predicted to be a passenger in this tumor type context.
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(CANCER) Cancer
(SOLID) Solid tumour
(S) Sarcoma
(UCS) Uterine carcinosarcoma
Driver
(OS) Osteosarcoma
Driver
(LEIS) Leiomyosarcoma
Driver
(UCEC) Endometrial cancer
Driver
(ST) Stomach adenocarcinoma
Driver
(LUNG_CANCER) Lung cancer
(SCLC) Small-cell lung cancer
Driver
(NSCLC) Non-small cell lung cancer
(LUSC) Lung squamous cell carcinoma
Passenger
(LUAD) Lung adenocarcinoma
Driver
(R) Kidney cancer
(RCH) Chromophobe renal cell carcinoma
Passenger
(RCCC) Renal clear cell carcinoma
Driver
(PRAD) Prostate adenocarcinoma
Driver
(CNS) Central nervous system cancer
(G) Glioma
(PIA) Pilocityc astrocytoma
Passenger
(LGG) Lower grade glioma
Passenger
(HGG) High-grade glioma
Driver
(GBM) Glioblastoma
Driver
(PA) Pancreatic cancer
(PAAD) Pancreas adenocarcinoma
Passenger
(OV) Ovary cancer
Passenger
(HNSC) Head and neck squamous cell carcinoma
Passenger
(LIVER) LIVER
(HC) Hepatic cancer
Driver
(ESCA) Esophageal cancer
Passenger
(COREAD) Colorectal adenocarcinoma
Passenger
(SKIN) Skin cancer
(CM) Cutaneous melanoma of the skin
Passenger
(CH) Cholangiocarcinoma
Driver
(BRCA) Breast adenocarcinoma
Passenger
(BLCA) Bladder cancer
Passenger
(NON_SOLID) Non-Solid cancer
(L) Lymphoid cancer
(LY) Lymphoma
(NHLY) Non-hodking lymphoma
Driver
(DLBCL) Diffuse large B-cell lymphoma
Driver
(LK) Leukemia
(CLL) Chronic lymphoblastic leukemia
Driver
(AML) Acute myeloid leukemia
Driver
(MM) Multiple myeloma
Driver