BoostDM

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Note: You're navigating the results of models obtained with the previous release of IntOGen (2020). A new boostDM version corresponding to the current IntOGen release will be available soon.

PTEN 10:87933194:G (F145L) ×

Driver potential

Model	BoostDM class	BoostDM score
(BRCA) Breast adenocarcinoma	Driver	0.62
(CM) Cutaneous melanoma of the skin	Passenger	0.42
(COREAD) Colorectal adenocarcinoma	Passenger	0.42
(GBM) Glioblastoma	Driver	0.62
(LUNG_CANCER) Lung cancer	Passenger	0.00
(PRAD) Prostate adenocarcinoma	Driver	0.62
(R) Kidney cancer	Passenger	0.42
(UCEC) Endometrial cancer	Driver	0.75

Select a tumor type to check the corresponding model Show the legend

Predictions cast with a model trained in this specific tumor type.

Predictions cast with a model trained with a more general tumor type, determined as the most recent underlined ancestor of the leaf.

Driver
The mutation is predicted to be a driver in this tumor type context.

Passenger
The mutation is predicted to be a passenger in this tumor type context.

(CANCER) Cancer
- (SOLID) Solid tumour
  - (UCEC) Endometrial cancer
    
    Driver
  - (R) Kidney cancer
    
    Passenger
  - (PRAD) Prostate adenocarcinoma
    
    Driver
  - (LUNG_CANCER) Lung cancer
    
    Passenger
  - (CNS) Central nervous system cancer
    - (G) Glioma
      - (GBM) Glioblastoma
        
        Driver
  - (COREAD) Colorectal adenocarcinoma
    
    Passenger
  - (SKIN) Skin cancer
    - (CM) Cutaneous melanoma of the skin
      
      Passenger
  - (BRCA) Breast adenocarcinoma
    
    Driver