BoostDM

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Note: You're navigating the results of models obtained with the previous release of IntOGen (2020). A new boostDM version corresponding to the current IntOGen release will be available soon.

PIK3CA 3:179209651:A (R401Q) ×

Driver potential

Model	BoostDM class	BoostDM score
(BLCA) Bladder cancer	Driver	0.64
(BRCA) Breast adenocarcinoma	Passenger	0.08
(CESC) Cervix squamous cancer	Passenger	0.18
(COREAD) Colorectal adenocarcinoma	Driver	0.90
(ESCA) Esophageal cancer	Driver	0.59
(GBM) Glioblastoma	Passenger	0.37
(HNSC) Head and neck squamous cell carcinoma	Passenger	0.35
(LGG) Lower grade glioma	Passenger	0.37
(LUAD) Lung adenocarcinoma	Passenger	0.11
(LUNG_CANCER) Lung cancer	Passenger	0.11
(PRAD) Prostate adenocarcinoma	Passenger	0.42
(S) Sarcoma	Passenger	0.11
(ST) Stomach adenocarcinoma	Driver	0.86
(UCEC) Endometrial cancer	Driver	0.91

Select a tumor type to check the corresponding model Show the legend

Predictions cast with a model trained in this specific tumor type.

Predictions cast with a model trained with a more general tumor type, determined as the most recent underlined ancestor of the leaf.

Driver
The mutation is predicted to be a driver in this tumor type context.

Passenger
The mutation is predicted to be a passenger in this tumor type context.

(CANCER) Cancer
- (SOLID) Solid tumour
  - (UCEC) Endometrial cancer
    
    Driver
  - (ST) Stomach adenocarcinoma
    
    Driver
  - (S) Sarcoma
    
    Passenger
  - (PRAD) Prostate adenocarcinoma
    
    Passenger
  - (LUNG_CANCER) Lung cancer
    - (NSCLC) Non-small cell lung cancer
      - (LUAD) Lung adenocarcinoma
        
        Passenger
  - (CNS) Central nervous system cancer
    - (G) Glioma
      - (LGG) Lower grade glioma
        
        Passenger
      - (GBM) Glioblastoma
        
        Passenger
  - (HNSC) Head and neck squamous cell carcinoma
    
    Passenger
  - (ESCA) Esophageal cancer
    
    Driver
  - (COREAD) Colorectal adenocarcinoma
    
    Driver
  - (CESC) Cervix squamous cancer
    
    Passenger
  - (BRCA) Breast adenocarcinoma
    
    Passenger
  - (BLCA) Bladder cancer
    
    Driver