BoostDM

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Note: You're navigating the results of models obtained with the previous release of IntOGen (2020). A new boostDM version corresponding to the current IntOGen release will be available soon.

KMT2D 12:49034933:A (L3412L) ×

Driver potential

Model	BoostDM class	BoostDM score
(BLCA) Bladder cancer	Driver	0.99
(CESC) Cervix squamous cancer	Passenger	0.01
(DLBCL) Diffuse large B-cell lymphoma	Driver	0.67
(HNSC) Head and neck squamous cell carcinoma	Driver	0.55
(LUNG_CANCER) Lung cancer	Driver	0.79
(LUSC) Lung squamous cell carcinoma	Driver	0.76
(LY) Lymphoma	Driver	0.92
(PRAD) Prostate adenocarcinoma	Passenger	0.01

Select a tumor type to check the corresponding model Show the legend

Predictions cast with a model trained in this specific tumor type.

Predictions cast with a model trained with a more general tumor type, determined as the most recent underlined ancestor of the leaf.

Driver
The mutation is predicted to be a driver in this tumor type context.

Passenger
The mutation is predicted to be a passenger in this tumor type context.

(CANCER) Cancer
- (SOLID) Solid tumour
  - (PRAD) Prostate adenocarcinoma
    
    Passenger
  - (LUNG_CANCER) Lung cancer
    - (NSCLC) Non-small cell lung cancer
      - (LUSC) Lung squamous cell carcinoma
        
        Driver
  - (HNSC) Head and neck squamous cell carcinoma
    
    Driver
  - (CESC) Cervix squamous cancer
    
    Passenger
  - (BLCA) Bladder cancer
    
    Driver
- (NON_SOLID) Non-Solid cancer
  - (L) Lymphoid cancer
    - (LY) Lymphoma
      - (DLBCL) Diffuse large B-cell lymphoma
        
        Driver