In silico saturation mutagenesis profiles across all tumor types where a reliable prediction is available. Red dots represent residue positions with at least one driver mutation in their respective codons according to boostDM. The dendrogram on the right represents a hierarchical clustering of the profiles based on site-by-site concordance via Matthews Correlation (MCC) similarity. The track on the top displays the Pfam domains. See the FAQs for more details about the in silico saturation mutagenesis computed with boostDM.