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CDKN2A LUNG_CANCER ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
9:21971187:A R58* stop_gained 1.00 0
9:21971030:T W110* stop_gained 1.00 0
9:21974749:A E27* stop_gained 1.00 0
9:21974731:A E33* stop_gained 1.00 0
9:21968749:T W160* stop_gained 0.99 0
9:21968753:T L159* stop_gained 0.99 0
9:21971029:T W110* stop_gained 0.99 0
9:21970914:A E149* stop_gained 0.99 0
9:21971178:A E61* stop_gained 0.99 0
9:21971001:A E120* stop_gained 0.99 0
9:21974793:T S12* stop_gained 0.99 0
9:21974752:A E26* stop_gained 0.99 0
9:21968763:A G156* stop_gained 0.99 0
9:21968742:A R163* stop_gained 0.98 0
9:21971143:T C72* stop_gained 0.98 0
9:21968743:T C162* stop_gained 0.98 0
9:21971121:A R80* stop_gained 0.98 0
9:21974824:A E2* stop_gained 0.98 0
9:21971004:A E119* stop_gained 0.98 0
9:21970947:A R138* stop_gained 0.98 0
9:21970904:T S152* stop_gained 0.98 0
9:21970904:C S152* stop_gained 0.98 0
9:21974783:T W15* stop_gained 0.98 0
9:21974696:T Y44* stop_gained 0.98 0
9:21974696:C Y44* stop_gained 0.98 0
9:21970972:T Y129* stop_gained 0.97 0
9:21970972:C Y129* stop_gained 0.97 0
9:21971154:A E69* stop_gained 0.97 0
9:21968750:T W160* stop_gained 0.97 0
9:21970902:A E153* stop_gained 0.97 0
9:21974784:T W15* stop_gained 0.97 0
9:21974800:A E10* stop_gained 0.97 0
9:21971097:A E88* stop_gained 0.97 0
9:21974680:A Q50* stop_gained 0.97 0
9:21971139:T D74N missense_variant 0.96 0
9:21971139:A D74Y missense_variant 0.96 0
9:21971139:G D74H missense_variant 0.96 0
9:21971037:A D108Y missense_variant 0.96 0
9:21971037:T D108N missense_variant 0.96 0
9:21971037:G D108H missense_variant 0.96 0
9:21971007:T A118T missense_variant 0.95 0
9:21971007:G A118P missense_variant 0.95 0
9:21971007:A A118S missense_variant 0.95 0
9:21971055:G A102P missense_variant 0.94 0
9:21971055:A A102S missense_variant 0.94 0
9:21971055:T A102T missense_variant 0.94 0
9:21971012:C D116G missense_variant 0.94 0
9:21971036:G D108A missense_variant 0.94 0
9:21971036:C D108G missense_variant 0.94 0
9:21971036:A D108V missense_variant 0.94 0
9:21971012:A D116V missense_variant 0.94 0
9:21971012:G D116A missense_variant 0.94 0
9:21971138:C D74G missense_variant 0.92 0
9:21971138:G D74A missense_variant 0.92 0
9:21971138:A D74V missense_variant 0.92 0
9:21971207:T V51D missense_variant 0.92 0
9:21971207:G V51A missense_variant 0.92 0
9:21971207:C V51G missense_variant 0.92 0
9:21971200:G M53I missense_variant 0.91 0
9:21971200:T M53I missense_variant 0.91 0
9:21971200:A M53I missense_variant 0.91 0
9:21971203:A M52I missense_variant 0.89 0
9:21971195:A G55V missense_variant 0.89 0
9:21971195:G G55A missense_variant 0.89 0
9:21971195:T G55D missense_variant 0.89 0
9:21971196:A G55C missense_variant 0.89 0
9:21971196:G G55R missense_variant 0.89 0
9:21971196:T G55S missense_variant 0.89 0
9:21971203:G M52I missense_variant 0.89 0
9:21971203:T M52I missense_variant 0.89 0
9:21971159:T G67D missense_variant 0.86 0
9:21974682:G I49T missense_variant 0.86 0
9:21974682:T I49N missense_variant 0.86 0
9:21971159:A G67V missense_variant 0.86 0
9:21971159:G G67A missense_variant 0.86 0
9:21974682:C I49S missense_variant 0.86 0
9:21974769:C A20G missense_variant 0.86 0
9:21974769:T A20E missense_variant 0.86 0
9:21974769:A A20V missense_variant 0.86 0
9:21971081:T T93K missense_variant 0.86 0
9:21971081:A T93M missense_variant 0.86 0
9:21971081:C T93R missense_variant 0.86 0
9:21974685:C P48R missense_variant 0.85 0
9:21974685:A P48L missense_variant 0.85 0
9:21974685:T P48Q missense_variant 0.85 0
9:21971106:A A85S missense_variant 0.84 0
9:21971106:T A85T missense_variant 0.84 0
9:21971109:G D84H missense_variant 0.84 0
9:21971109:A D84Y missense_variant 0.84 0
9:21971109:T D84N missense_variant 0.84 0
9:21971099:A R87L missense_variant 0.84 0
9:21971099:G R87P missense_variant 0.84 0
9:21971099:T R87Q missense_variant 0.84 0
9:21971106:G A85P missense_variant 0.84 0
9:21971082:G T93P missense_variant 0.84 0
9:21971082:C T93A missense_variant 0.84 0
9:21971082:A T93S missense_variant 0.84 0
9:21974680:T Q50K missense_variant 0.84 0
9:21974680:C Q50E missense_variant 0.84 0
9:21971208:A V51F missense_variant 0.84 0
9:21971160:T G67S missense_variant 0.84 0
9:21971160:A G67C missense_variant 0.84 0
9:21971208:T V51I missense_variant 0.84 0
9:21971208:G V51L missense_variant 0.84 0
9:21971160:G G67R missense_variant 0.84 0
9:21971078:G L94P missense_variant 0.83 0
9:21971078:C L94R missense_variant 0.83 0
9:21971078:T L94Q missense_variant 0.83 0
9:21970982:C V126G missense_variant 0.83 0
9:21970982:G V126A missense_variant 0.83 0
9:21970982:T V126D missense_variant 0.83 0
9:21971183:C V59G missense_variant 0.82 0
9:21971183:T V59E missense_variant 0.82 0
9:21971183:G V59A missense_variant 0.82 0
9:21974781:G L16P missense_variant 0.82 0
9:21974781:C L16R missense_variant 0.82 0
9:21974781:T L16Q missense_variant 0.82 0
9:21971147:A N71I missense_variant 0.80 0
9:21971147:C N71S missense_variant 0.80 0
9:21971147:G N71T missense_variant 0.80 0
9:21971006:T A118D missense_variant 0.79 0
9:21971006:C A118G missense_variant 0.79 0
9:21971006:A A118V missense_variant 0.79 0
9:21971054:C A102G missense_variant 0.79 0
9:21971054:T A102E missense_variant 0.79 0
9:21971054:A A102V missense_variant 0.79 0
9:21971157:T A68T missense_variant 0.78 0
9:21971157:G A68P missense_variant 0.78 0
9:21971157:A A68S missense_variant 0.78 0
9:21971198:G M54T missense_variant 0.78 0
9:21971171:C L63R missense_variant 0.78 0
9:21971171:G L63P missense_variant 0.78 0
9:21971171:T L63Q missense_variant 0.78 0
9:21971198:C M54R missense_variant 0.78 0
9:21971198:T M54K missense_variant 0.78 0
9:21971181:G A60P missense_variant 0.76 0
9:21971181:T A60T missense_variant 0.76 0
9:21971181:A A60S missense_variant 0.76 0
9:21974679:C Q50R missense_variant 0.75 0
9:21974679:G Q50P missense_variant 0.75 0
9:21974679:A Q50L missense_variant 0.75 0
9:21971111:A H83L missense_variant 0.75 0
9:21971108:A D84V missense_variant 0.75 0
9:21971108:G D84A missense_variant 0.75 0
9:21971108:C D84G missense_variant 0.75 0
9:21971111:G H83P missense_variant 0.75 0
9:21971111:C H83R missense_variant 0.75 0
9:21971172:T L63M missense_variant 0.74 0
9:21971172:C L63V missense_variant 0.74 0
9:21971019:C P114A missense_variant 0.73 0
9:21971019:T P114T missense_variant 0.73 0
9:21971018:T P114H missense_variant 0.73 0
9:21971018:C P114R missense_variant 0.73 0
9:21971018:A P114L missense_variant 0.73 0
9:21971019:A P114S missense_variant 0.73 0
9:21974678:G Q50H missense_variant 0.73 0
9:21974678:A Q50H missense_variant 0.73 0
9:21974770:G A20P missense_variant 0.73 0
9:21974770:A A20S missense_variant 0.73 0
9:21974770:T A20T missense_variant 0.73 0
9:21971117:T P81H missense_variant 0.73 0
9:21971117:A P81L missense_variant 0.73 0
9:21971117:C P81R missense_variant 0.73 0
9:21971118:A P81S missense_variant 0.73 0
9:21971118:T P81T missense_variant 0.73 0
9:21971118:C P81A missense_variant 0.73 0
9:21971085:T D92N missense_variant 0.72 0
9:21971085:A D92Y missense_variant 0.72 0
9:21971085:G D92H missense_variant 0.72 0
9:21971093:A G89V missense_variant 0.67 0
9:21971103:T A86T missense_variant 0.67 0
9:21971103:G A86P missense_variant 0.67 0
9:21971103:A A86S missense_variant 0.67 0
9:21971094:T G89S missense_variant 0.67 0
9:21971094:G G89R missense_variant 0.67 0
9:21971094:A G89C missense_variant 0.67 0
9:21971093:T G89D missense_variant 0.67 0
9:21971093:G G89A missense_variant 0.67 0
9:21970992:A H123Y missense_variant 0.65 0
9:21970992:T H123N missense_variant 0.65 0
9:21970992:C H123D missense_variant 0.65 0
9:21974766:T A21D missense_variant 0.64 0
9:21974766:C A21G missense_variant 0.64 0
9:21974766:A A21V missense_variant 0.64 0
9:21971150:A P70L missense_variant 0.63 0
9:21971156:T A68E missense_variant 0.63 0
9:21971150:T P70H missense_variant 0.63 0
9:21971156:A A68V missense_variant 0.63 0
9:21971150:C P70R missense_variant 0.63 0
9:21971156:C A68G missense_variant 0.63 0
9:21971168:C L64R missense_variant 0.62 0
9:21971204:C M52R missense_variant 0.62 0
9:21971204:G M52T missense_variant 0.62 0
9:21971204:T M52K missense_variant 0.62 0
9:21971168:T L64Q missense_variant 0.62 0
9:21971168:G L64P missense_variant 0.62 0
9:21971069:T L97Q missense_variant 0.62 0
9:21971069:C L97R missense_variant 0.62 0
9:21971069:G L97P missense_variant 0.62 0
9:21971009:T L117Q missense_variant 0.62 0
9:21971009:C L117R missense_variant 0.62 0
9:21971009:G L117P missense_variant 0.62 0
9:21974767:G A21P missense_variant 0.62 0
9:21974767:T A21T missense_variant 0.62 0
9:21974767:A A21S missense_variant 0.62 0
9:21971015:C V115G missense_variant 0.62 0
9:21971015:G V115A missense_variant 0.62 0
9:21971015:T V115E missense_variant 0.62 0
9:21971153:G E69A missense_variant 0.62 0
9:21971153:C E69G missense_variant 0.62 0
9:21971153:A E69V missense_variant 0.62 0
9:21971151:A P70S missense_variant 0.60 0
9:21971151:T P70T missense_variant 0.60 0
9:21971151:C P70A missense_variant 0.60 0
9:21970974:C Y129D missense_variant 0.60 0
9:21970974:T Y129N missense_variant 0.60 0
9:21970974:G Y129H missense_variant 0.60 0
9:21971110:C H83Q missense_variant 0.59 0
9:21971110:T H83Q missense_variant 0.59 0
9:21971011:C D116E missense_variant 0.59 0
9:21971011:T D116E missense_variant 0.59 0
9:21971180:C A60G missense_variant 0.58 0
9:21971180:T A60E missense_variant 0.58 0
9:21971180:A A60V missense_variant 0.58 0
9:21971112:T H83N missense_variant 0.58 0
9:21971112:A H83Y missense_variant 0.58 0
9:21971112:C H83D missense_variant 0.58 0
9:21971169:T L64M missense_variant 0.57 0
9:21971169:C L64V missense_variant 0.57 0
9:21974695:T G45S missense_variant 0.57 0
9:21974695:G G45R missense_variant 0.57 0
9:21974695:A G45C missense_variant 0.57 0
9:21974694:T G45D missense_variant 0.57 0
9:21974694:G G45A missense_variant 0.57 0
9:21974694:A G45V missense_variant 0.57 0
9:21970970:G L130P missense_variant 0.56 0
9:21970970:T L130Q missense_variant 0.56 0
9:21970970:C L130R missense_variant 0.56 0
9:21971067:C H98D missense_variant 0.55 0
9:21971067:T H98N missense_variant 0.55 0
9:21971067:A H98Y missense_variant 0.55 0
9:21971091:T F90I missense_variant 0.54 0
9:21971091:C F90V missense_variant 0.54 0
9:21971091:G F90L missense_variant 0.54 0
9:21974761:T G23S missense_variant 0.51 0
9:21974761:G G23R missense_variant 0.51 0
9:21974761:A G23C missense_variant 0.51 0
9:21974773:T A19T missense_variant 0.51 0
9:21974773:G A19P missense_variant 0.51 0
9:21974773:A A19S missense_variant 0.51 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(LUNG_CANCER) Lung cancer LUNG_CANCER 0.51 0.14