BoostDM

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Note: You're navigating the results of models obtained with the previous release of IntOGen (2020). A new boostDM version corresponding to the current IntOGen release will be available soon.

BRAF 7:140754204:A (R575I) ×

Driver potential

Model	BoostDM class	BoostDM score
(CM) Cutaneous melanoma of the skin	Driver	0.97
(COREAD) Colorectal adenocarcinoma	Passenger	0.06
(LUAD) Lung adenocarcinoma	Passenger	0.19
(LUNG_CANCER) Lung cancer	Passenger	0.11
(MM) Multiple myeloma	Passenger	0.01
(THCA) Thyroid adenocarcinoma	Passenger	0.00

Select a tumor type to check the corresponding model Show the legend

Predictions cast with a model trained in this specific tumor type.

Predictions cast with a model trained with a more general tumor type, determined as the most recent underlined ancestor of the leaf.

Driver
The mutation is predicted to be a driver in this tumor type context.

Passenger
The mutation is predicted to be a passenger in this tumor type context.

(CANCER) Cancer
- (SOLID) Solid tumour
  - (THCA) Thyroid adenocarcinoma
    
    Passenger
  - (LUNG_CANCER) Lung cancer
    - (NSCLC) Non-small cell lung cancer
      - (LUAD) Lung adenocarcinoma
        
        Passenger
  - (COREAD) Colorectal adenocarcinoma
    
    Passenger
  - (SKIN) Skin cancer
    - (CM) Cutaneous melanoma of the skin
      
      Driver
- (NON_SOLID) Non-Solid cancer
  - (MM) Multiple myeloma
    
    Passenger