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ZP4 has not been detected as a mutational cancer driver

ZP4
Ensembl id ENSG00000116996
Mutated samples
Coding Sequence 115 (1.7%)
Protein Affecting 82 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZP4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 33 21 5.37
Cutaneous melanoma No 18 12 3.25
Breast carcinoma No 11 9 0.78
Lung squamous cell carcinoma No 8 7 4.02
Stomach adenocarcinoma No 5 5 3.11
Head and neck squamous cell carcinoma No 5 5 1.33
Uterine corpus endometrioid carcinoma No 4 4 1.74
Glioblastoma multiforme No 6 4 1.06
Renal clear cell carcinoma No 3 3 0.72
Hepatocarcinoma No 2 2 2.22
Neuroblastoma No 2 2 0.95
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 4 1 1.02
Medulloblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 3 1 0.34
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 2 1 0.68
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 2 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence