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ZBBX has not been detected as a mutational cancer driver

ZBBX
Ensembl id ENSG00000169064
Mutated samples
Coding Sequence 150 (2.2%)
Protein Affecting 118 (1.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ZBBX gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 49 40 10.84
Lung squamous cell carcinoma No 17 17 9.77
Lung adenocarcinoma No 13 13 3.32
Head and neck squamous cell carcinoma No 6 6 1.60
Renal clear cell carcinoma No 6 5 1.20
Stomach adenocarcinoma No 7 5 3.11
Small cell lung carcinoma No 5 5 7.25
Breast carcinoma No 7 4 0.35
Glioblastoma multiforme No 4 4 1.06
Hepatocarcinoma No 4 2 2.22
Uterine corpus endometrioid carcinoma No 5 2 0.87
Chronic lymphocytic leukemia No 7 2 0.69
Multiple myeloma No 2 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Esophageal carcinoma No 3 2 1.37
Acute lymphocytic leukemia No 2 2 1.64
Prostate adenocarcinoma No 2 1 0.41
Bladder carcinoma No 2 1 1.02
Thyroid carcinoma No 1 1 0.31
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 2 1 0.32
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence