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WNT7A has not been detected as a mutational cancer driver

WNT7A
Ensembl id ENSG00000154764
Mutated samples
Coding Sequence 63 (0.9%)
Protein Affecting 39 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all WNT7A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 14 3.79
Lung adenocarcinoma No 6 5 1.28
Breast carcinoma No 6 5 0.44
Lung squamous cell carcinoma No 4 3 1.72
Serous ovarian adenocarcinoma No 3 2 0.63
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Bladder carcinoma No 1 1 1.02
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 3 1 0.62
Esophageal carcinoma No 2 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence