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WDR33 has not been detected as a mutational cancer driver

WDR33
Ensembl id ENSG00000136709
Mutated samples
Coding Sequence 93 (1.4%)
Protein Affecting 72 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all WDR33 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 29 22 5.96
Breast carcinoma No 9 8 0.70
Stomach adenocarcinoma No 8 7 4.35
Lung squamous cell carcinoma No 6 5 2.87
Bladder carcinoma No 4 4 4.08
Uterine corpus endometrioid carcinoma No 5 4 1.74
Head and neck squamous cell carcinoma No 4 4 1.07
Lower grade glioma No 3 3 1.78
Lung adenocarcinoma No 7 2 0.51
Renal clear cell carcinoma No 3 2 0.48
Thyroid carcinoma No 2 2 0.62
Glioblastoma multiforme No 2 2 0.53
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 2 1 0.41
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence