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USP9X has not been detected as a mutational cancer driver

USP9X
Ensembl id ENSG00000124486
Mutated samples
Coding Sequence 137 (2.0%)
Protein Affecting 107 (1.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all USP9X gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 17 4.61
Uterine corpus endometrioid carcinoma No 19 14 6.09
Head and neck squamous cell carcinoma No 17 14 3.73
Breast carcinoma No 16 13 1.13
Lung adenocarcinoma No 15 12 3.07
Lung squamous cell carcinoma No 9 8 4.60
Stomach adenocarcinoma No 7 5 3.11
Renal clear cell carcinoma No 6 4 0.96
Thyroid carcinoma No 5 4 1.24
Bladder carcinoma No 3 3 3.06
Glioblastoma multiforme No 3 2 0.53
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 1 1 1.11
Acute myeloid leukemia No 2 1 0.51
Medulloblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 2 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 2 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 2 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Pancreas adenocarcinoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence