Top
UNC80 has not been detected as a mutational cancer driver

UNC80
Ensembl id ENSG00000144406
Mutated samples
Coding Sequence 85 (1.3%)
Protein Affecting 58 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all UNC80 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 11 9 0.78
Uterine corpus endometrioid carcinoma No 10 8 3.48
Lung adenocarcinoma No 8 7 1.79
Lung squamous cell carcinoma No 4 4 2.30
Cutaneous melanoma No 7 4 1.08
Head and neck squamous cell carcinoma No 7 4 1.07
Acute lymphocytic leukemia No 4 4 3.28
Renal clear cell carcinoma No 6 3 0.72
Prostate adenocarcinoma No 2 2 0.82
Chronic lymphocytic leukemia No 7 2 0.69
Multiple myeloma No 3 2 2.90
Esophageal carcinoma No 3 2 1.37
Hepatocarcinoma No 1 1 1.11
Thyroid carcinoma No 1 1 0.31
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 5 1 0.62
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Acute myeloid leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence