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TUBA3E has not been detected as a mutational cancer driver

TUBA3E
Ensembl id ENSG00000152086
Mutated samples
Coding Sequence 34 (0.5%)
Protein Affecting 23 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TUBA3E gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 4 4 1.08
Lung squamous cell carcinoma No 4 3 1.72
Esophageal carcinoma No 3 3 2.05
Lung adenocarcinoma No 3 2 0.51
Stomach adenocarcinoma No 3 2 1.24
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 2 1 0.09
Uterine corpus endometrioid carcinoma No 4 1 0.43
Neuroblastoma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence