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TRAK1 has not been detected as a mutational cancer driver

TRAK1
Ensembl id ENSG00000182606
Mutated samples
Coding Sequence 69 (1.0%)
Protein Affecting 43 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TRAK1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 21 11 2.98
Lung adenocarcinoma No 6 5 1.28
Breast carcinoma No 6 5 0.44
Uterine corpus endometrioid carcinoma No 4 4 1.74
Stomach adenocarcinoma No 7 3 1.86
Head and neck squamous cell carcinoma No 5 3 0.80
Prostate adenocarcinoma No 2 2 0.82
Bladder carcinoma No 2 2 2.04
Medulloblastoma No 1 1 0.48
Lung squamous cell carcinoma No 1 1 0.57
Renal clear cell carcinoma No 1 1 0.24
Neuroblastoma No 1 1 0.48
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 3 1 0.26
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence