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TNS1 has not been detected as a mutational cancer driver

TNS1
Ensembl id ENSG00000079308
Mutated samples
Coding Sequence 123 (1.8%)
Protein Affecting 94 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TNS1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 13 12 3.07
Cutaneous melanoma No 20 11 2.98
Stomach adenocarcinoma No 12 10 6.21
Colorectal adenocarcinoma No 8 7 3.06
Prostate adenocarcinoma No 6 6 2.47
Breast carcinoma No 9 6 0.52
Uterine corpus endometrioid carcinoma No 10 6 2.61
Head and neck squamous cell carcinoma No 7 6 1.60
Bladder carcinoma No 4 4 4.08
Lung squamous cell carcinoma No 5 4 2.30
Renal clear cell carcinoma No 4 4 0.96
Thyroid carcinoma No 4 3 0.93
Serous ovarian adenocarcinoma No 3 3 0.95
Small cell lung carcinoma No 3 3 4.35
Glioblastoma multiforme No 3 3 0.79
Esophageal carcinoma No 4 3 2.05
Hepatocarcinoma No 2 1 1.11
Medulloblastoma No 1 1 0.48
Multiple myeloma No 2 1 1.45
Chronic lymphocytic leukemia No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence