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TNNI3K has not been detected as a mutational cancer driver

TNNI3K
Ensembl id ENSG00000116783
Mutated samples
Coding Sequence 155 (2.3%)
Protein Affecting 86 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TNNI3K gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 36 27 7.32
Lung adenocarcinoma No 15 12 3.07
Lung squamous cell carcinoma No 18 9 5.17
Stomach adenocarcinoma No 11 5 3.11
Colorectal adenocarcinoma No 8 5 2.18
Esophageal carcinoma No 6 5 3.42
Small cell lung carcinoma No 9 4 5.80
Uterine corpus endometrioid carcinoma No 5 3 1.30
Serous ovarian adenocarcinoma No 4 3 0.95
Head and neck squamous cell carcinoma No 6 3 0.80
Bladder carcinoma No 6 2 2.04
Renal clear cell carcinoma No 4 2 0.48
Lower grade glioma No 3 2 1.18
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 2 1 1.11
Glioblastoma multiforme No 2 1 0.26
Acute lymphocytic leukemia No 2 1 0.82
Breast carcinoma No 4 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 7 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence