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TESK2 has not been detected as a mutational cancer driver

TESK2
Ensembl id ENSG00000070759
Mutated samples
Coding Sequence 65 (1.0%)
Protein Affecting 24 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TESK2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 6 1.63
Uterine corpus endometrioid carcinoma No 8 4 1.74
Breast carcinoma No 6 2 0.17
Lung squamous cell carcinoma No 4 2 1.15
Lung adenocarcinoma No 4 1 0.26
Bladder carcinoma No 1 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 2 1 0.32
Stomach adenocarcinoma No 3 1 0.62
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 4 1 0.27
Glioblastoma multiforme No 4 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 3 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence