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TDRD10 has not been detected as a mutational cancer driver

TDRD10
Ensembl id ENSG00000163239
Mutated samples
Coding Sequence 71 (1.0%)
Protein Affecting 32 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TDRD10 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 5 1.36
Renal clear cell carcinoma No 5 4 0.96
Lung adenocarcinoma No 5 3 0.77
Stomach adenocarcinoma No 3 3 1.86
Head and neck squamous cell carcinoma No 10 3 0.80
Breast carcinoma No 9 2 0.17
Lung squamous cell carcinoma No 3 2 1.15
Uterine corpus endometrioid carcinoma No 4 2 0.87
Glioblastoma multiforme No 5 2 0.53
Acute myeloid leukemia No 1 1 0.51
Neuroblastoma No 1 1 0.48
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 2 1 0.32
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Bladder carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence