IntOGen - TAL1 gene cancer mutations

TAL1 is detected as a mutational cancer driver

TAL1 reports

Methods
Mutation distribution

Gene details

TAL1
Ensembl ID ENSG00000162367 Transcript ID ENST00000294339 Protein ID ENSP00000294339
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 5 Mutations 180
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence