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TAF1A has not been detected as a mutational cancer driver

TAF1A
Ensembl id ENSG00000143498
Mutated samples
Coding Sequence 31 (0.5%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TAF1A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 14 3.79
Lung adenocarcinoma No 5 4 1.02
Renal clear cell carcinoma No 3 3 0.72
Lung squamous cell carcinoma No 2 2 1.15
Hepatocarcinoma No 1 1 1.11
Non small cell lung carcinoma No 1 1 3.23
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Bladder carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence