IntOGen - SMARCB1 gene cancer mutations

SMARCB1 is detected as a mutational cancer driver

SMARCB1 reports

Methods
Mutation distribution

Gene details

SMARCB1
Gene ID ENSG00000099956 Transcript ID ENST00000644036 Protein ID ENSP00000494049
Cancer types where is driver 5 Cohorts where is driver 5 Mutated samples 13 Mutations 185
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence