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SLITRK2 has not been detected as a mutational cancer driver

SLITRK2
Ensembl id ENSG00000185985
Mutated samples
Coding Sequence 143 (2.1%)
Protein Affecting 96 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLITRK2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 30 22 5.63
Head and neck squamous cell carcinoma No 14 11 2.93
Cutaneous melanoma No 13 9 2.44
Lung squamous cell carcinoma No 9 8 4.60
Stomach adenocarcinoma No 11 7 4.35
Uterine corpus endometrioid carcinoma No 8 6 2.61
Breast carcinoma No 9 5 0.44
Small cell lung carcinoma No 5 5 7.25
Esophageal carcinoma No 9 5 3.42
Serous ovarian adenocarcinoma No 4 4 1.27
Colorectal adenocarcinoma No 7 3 1.31
Glioblastoma multiforme No 5 3 0.79
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 3 1 1.11
Pancreas adenocarcinoma No 2 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 1 1 0.59
Diffuse B cell lymphoma No 1 1 4.35
Acute lymphocytic leukemia No 1 1 0.82
Medulloblastoma No 4 0 0.00
Neuroblastoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence