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SLC44A3 has not been detected as a mutational cancer driver

SLC44A3
Ensembl id ENSG00000143036
Mutated samples
Coding Sequence 45 (0.7%)
Protein Affecting 26 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC44A3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 8 5 1.36
Stomach adenocarcinoma No 5 3 1.86
Breast carcinoma No 5 2 0.17
Renal clear cell carcinoma No 3 2 0.48
Glioblastoma multiforme No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Lung adenocarcinoma No 6 1 0.26
Bladder carcinoma No 2 1 1.02
Lung squamous cell carcinoma No 1 1 0.57
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Chronic lymphocytic leukemia No 1 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 1 1 0.27
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence