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SLC15A2 has not been detected as a mutational cancer driver

SLC15A2
Ensembl id ENSG00000163406
Mutated samples
Coding Sequence 96 (1.4%)
Protein Affecting 65 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC15A2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 51 32 8.67
Head and neck squamous cell carcinoma No 7 6 1.60
Lung squamous cell carcinoma No 4 4 2.30
Stomach adenocarcinoma No 5 4 2.48
Esophageal carcinoma No 4 4 2.74
Lung adenocarcinoma No 5 3 0.77
Renal clear cell carcinoma No 4 3 0.72
Breast carcinoma No 2 2 0.17
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 2 1 1.02
Uterine corpus endometrioid carcinoma No 1 1 0.43
Chronic lymphocytic leukemia No 2 1 0.34
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 2 1 0.26
Hepatocarcinoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence