IntOGen - SGK1 gene cancer mutations

SGK1 is detected as a mutational cancer driver

SGK1 reports

Methods
Mutation distribution

Gene details

SGK1
Ensembl ID ENSG00000118515 Transcript ID ENST00000367858 Protein ID ENSP00000356832
Cancer types where is driver 4 Cohorts where is driver 6 Mutated samples 65 Mutations 467
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence