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SF3B1 × Pancreatic Adenocarcinoma ×

SF3B1 is detected as a mutational cancer driver in Pancreatic Adenocarcinoma

SF3B1 reports in Pancreatic Adenocarcinoma (PAAD)

Cancer type details
Pancreatic Adenocarcinoma
Cohorts 7
Samples 922
Mutations 2,520,434
Driver genes 64
Gene details
SF3B1
Ensembl ID ENSG00000115524
Transcript ID ENST00000335508
Protein ID ENSP00000335321
Cohorts where is driver 1
Mutated samples 6
Mutated samples (%) 0.65
Mutations 16
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence