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SERPINE2 has not been detected as a mutational cancer driver

SERPINE2
Ensembl id ENSG00000135919
Mutated samples
Coding Sequence 29 (0.4%)
Protein Affecting 17 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SERPINE2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 4 4 1.02
Cutaneous melanoma No 4 3 0.81
Breast carcinoma No 3 2 0.17
Stomach adenocarcinoma No 3 2 1.24
Bladder carcinoma No 1 1 1.02
Lung squamous cell carcinoma No 2 1 0.57
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 1 1 0.27
Glioblastoma multiforme No 2 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Neuroblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence