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SCG2 has not been detected as a mutational cancer driver

SCG2
Ensembl id ENSG00000171951
Mutated samples
Coding Sequence 59 (0.9%)
Protein Affecting 46 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SCG2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 11 9 2.30
Cutaneous melanoma No 14 9 2.44
Head and neck squamous cell carcinoma No 6 5 1.33
Renal clear cell carcinoma No 4 4 0.96
Stomach adenocarcinoma No 5 4 2.48
Bladder carcinoma No 3 3 3.06
Breast carcinoma No 2 2 0.17
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 2 2 0.53
Esophageal carcinoma No 3 2 1.37
Lung squamous cell carcinoma No 1 1 0.57
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Colorectal adenocarcinoma No 1 1 0.44
Uterine corpus endometrioid carcinoma No 2 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence