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SATB1 has not been detected as a mutational cancer driver

SATB1
Ensembl id ENSG00000182568
Mutated samples
Coding Sequence 70 (1.0%)
Protein Affecting 45 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SATB1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 20 15 4.07
Uterine corpus endometrioid carcinoma No 10 8 3.48
Lung adenocarcinoma No 5 5 1.28
Head and neck squamous cell carcinoma No 6 5 1.33
Breast carcinoma No 6 4 0.35
Lung squamous cell carcinoma No 5 3 1.72
Stomach adenocarcinoma No 4 3 1.86
Colorectal adenocarcinoma No 2 1 0.44
Esophageal carcinoma No 2 1 0.68
Hepatocarcinoma No 3 0 0.00
Bladder carcinoma No 1 0 0.00
Medulloblastoma No 3 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence