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SAMD7 has not been detected as a mutational cancer driver

SAMD7
Ensembl id ENSG00000187033
Mutated samples
Coding Sequence 81 (1.2%)
Protein Affecting 60 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SAMD7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 41 28 7.59
Lung adenocarcinoma No 11 10 2.56
Head and neck squamous cell carcinoma No 7 6 1.60
Lung squamous cell carcinoma No 4 3 1.72
Bladder carcinoma No 2 2 2.04
Stomach adenocarcinoma No 3 2 1.24
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 2 2 0.53
Breast carcinoma No 2 1 0.09
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 1 1 0.43
Serous ovarian adenocarcinoma No 1 1 0.32
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence