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RPS6KA3 has not been detected as a mutational cancer driver

RPS6KA3
Ensembl id ENSG00000177189
Mutated samples
Coding Sequence 44 (0.6%)
Protein Affecting 30 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RPS6KA3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 7 6 2.61
Hepatocarcinoma No 6 5 5.56
Breast carcinoma No 6 5 0.44
Head and neck squamous cell carcinoma No 3 3 0.80
Bladder carcinoma No 2 2 2.04
Cutaneous melanoma No 8 2 0.54
Lung adenocarcinoma No 2 1 0.26
Lung squamous cell carcinoma No 2 1 0.57
Neuroblastoma No 1 1 0.48
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Chronic lymphocytic leukemia No 2 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence