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RNF13 has not been detected as a mutational cancer driver

RNF13
Ensembl id ENSG00000082996
Mutated samples
Coding Sequence 29 (0.4%)
Protein Affecting 15 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RNF13 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach adenocarcinoma No 4 3 1.86
Breast carcinoma No 3 2 0.17
Lung squamous cell carcinoma No 3 2 1.15
Cutaneous melanoma No 4 2 0.54
Head and neck squamous cell carcinoma No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Lung adenocarcinoma No 2 1 0.26
Uterine corpus endometrioid carcinoma No 3 1 0.43
Serous ovarian adenocarcinoma No 1 1 0.32
Renal clear cell carcinoma No 2 0 0.00
Multiple myeloma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence