REG3A has not been detected as a mutational cancer driver

Ensembl id ENSG00000172016
Mutated samples
Coding Sequence 74 (1.1%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all REG3A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 15 13 3.32
Lung squamous cell carcinoma No 13 11 6.32
Cutaneous melanoma No 21 6 1.63
Head and neck squamous cell carcinoma No 5 4 1.07
Breast carcinoma No 4 3 0.26
Small cell lung carcinoma No 4 3 4.35
Colorectal adenocarcinoma No 2 2 0.87
Non small cell lung carcinoma No 2 1 3.23
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Esophageal carcinoma No 4 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence